Tarja Malm Selected Research

proteoglycan-degrading metalloendopeptidases

1/2016

ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis.

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Tarja Malm Research Topics

Disease

39	Alzheimer Disease (Alzheimer's Disease) 02/2024 - 06/2006
22	Inflammation (Inflammations) 03/2024 - 06/2006
19	Neuroinflammatory Diseases 07/2023 - 01/2011
12	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2024 - 06/2011
12	Stroke (Strokes) 01/2023 - 08/2013
6	Brain Ischemia (Cerebral Ischemia) 10/2019 - 01/2007
5	Ischemia 01/2022 - 07/2014
5	Migraine Disorders (Migraine) 01/2022 - 12/2017
5	Spinal Cord Injuries (Spinal Cord Injury) 01/2016 - 01/2007
4	Hypoxia (Hypoxemia) 01/2022 - 07/2008
4	Ischemic Stroke 06/2020 - 01/2017
4	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2019 - 08/2013
4	Infarction (Infarctions) 12/2017 - 08/2013
4	Gliosis 02/2015 - 06/2006
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 06/2019 - 01/2007
2	Encephalitis (Encephalitis, Rasmussen) 03/2024 - 01/2018
2	Central Nervous System Diseases (CNS Diseases) 01/2022 - 01/2016
2	Infections 12/2021 - 10/2013
2	Cognitive Dysfunction 08/2021 - 08/2021
2	Memory Disorders (Memory Loss) 08/2021 - 01/2019
2	Disease Progression 01/2020 - 06/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2019
2	Parkinson Disease (Parkinson's Disease) 01/2020 - 12/2014
2	Wounds and Injuries (Trauma) 06/2019 - 02/2015
2	Amyloid Plaque 01/2019 - 01/2008
2	Pain (Aches) 01/2019 - 01/2019
2	Neoplasms (Cancer) 12/2017 - 11/2015
2	Brain Injuries (Brain Injury) 01/2017 - 08/2013
2	Arthritis (Polyarthritis) 01/2016 - 01/2007
2	Demyelinating Diseases (Demyelinating Disease) 02/2015 - 03/2014
2	Contusions 02/2015 - 03/2014
2	Primary Immunodeficiency Diseases 05/2012 - 12/2010
1	Insulin Resistance 03/2024
1	Obesity 03/2024
1	Body Weight (Weight, Body) 01/2024
1	Brain Diseases (Brain Disorder) 09/2022
1	Dementia (Dementias) 01/2022
1	Amyloidosis 08/2021
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2020
1	Parkinsonian Disorders (Parkinsonism) 01/2020
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2020

Drug/Important Bio-Agent (IBA)

16	Amyloid (Amyloid Fibrils)IBA 07/2023 - 09/2009
13	Amyloid beta-PeptidesIBA 06/2022 - 06/2006
10	Proteins (Proteins, Gene)FDA Link 12/2022 - 01/2011
9	Peptides (Polypeptides)IBA 12/2022 - 06/2006
6	MicroRNAs (MicroRNA)IBA 10/2022 - 07/2008
5	LipopolysaccharidesIBA 11/2022 - 01/2018
5	CytokinesIBA 09/2022 - 10/2013
5	Transcription Factors (Transcription Factor)IBA 08/2016 - 01/2007
4	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 10/2019
4	Particulate MatterIBA 02/2024 - 01/2020
3	Apolipoprotein E4IBA 07/2023 - 08/2013
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2016
3	CopperIBA 09/2022 - 01/2017
3	Adenosine Triphosphate (ATP)IBA 01/2020 - 01/2018
3	CholesterolIBA 10/2019 - 08/2013
3	Interleukin-33IBA 06/2019 - 02/2015
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 04/2015 - 12/2014
3	Intravenous Immunoglobulins (IVIG)FDA Link 04/2014 - 12/2010
2	Insulin (Novolin)FDA Link 03/2024 - 02/2021
2	ApolipoproteinsIBA 07/2023 - 08/2013
2	Apolipoproteins E (ApoE)IBA 07/2023 - 08/2013
2	MetallothioneinIBA 09/2022 - 01/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 12/2017
2	AcidsIBA 01/2022 - 08/2021
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2019
2	Tissue Plasminogen Activator (Alteplase)FDA Link 06/2020 - 12/2017
2	(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acidIBA 01/2019 - 01/2015
2	LipidsIBA 12/2017 - 08/2013
2	Glutamic Acid (Glutamate)FDA Link 12/2017 - 01/2015
2	NF-kappa B (NF-kB)IBA 08/2016 - 01/2007
2	prolinedithiocarbamate (PDTC)IBA 02/2016 - 01/2007
2	EnzymesIBA 01/2016 - 01/2011
2	AntibodiesIBA 05/2012 - 12/2010
2	Glycogen Synthase (Synthase I)IBA 01/2011 - 01/2011
1	(R)- (11C)1- (2- chlorophenyl)- N- methyl- N- (1- methylpropyl)- 3- isoquinolinecarboxamideIBA 03/2024
1	Complement System Proteins (Complement)IBA 07/2023
1	Chemotactic FactorsIBA 09/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022
1	IsoenzymesIBA 01/2022
1	Air Pollutants (Pollutants, Air)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2022
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 12/2021
1	Member 2 Subfamily G ATP Binding Cassette TransporterIBA 12/2021
1	Ionotropic Glutamate ReceptorsIBA 12/2021
1	Neuroprotective AgentsIBA 10/2021
1	IronIBA 08/2021
1	florbetapirIBA 08/2021
1	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 08/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2020
1	Protein AggregatesIBA 01/2020
1	Chemokine CCL5IBA 01/2020
1	C-Reactive ProteinIBA 01/2020
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2020

Therapy/Procedure

9	Therapeutics 09/2022 - 01/2011
2	Immunomodulation 02/2021 - 10/2015
1	Cell- and Tissue-Based Therapy (Cell Therapy) 02/2021
1	Thrombectomy 06/2020
1	Activities of Daily Living (ADL) 01/2020